Research Topic · Peer-Reviewed

Free Radicals and Oxidative Stress

Free radicals are highly reactive molecules with unpaired electrons that can damage cellular components, while oxidative stress occurs when the production of these reactive species overwhelms the body's antioxidant defenses. Research published in Antioxidant Activity examines this imbalance through diverse experimen…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 92× across the literature 🔖 ISSN 2471-2140 🗓 Reviewed October 2026

Overview

Free radicals are highly reactive molecules with unpaired electrons that can damage cellular components, while oxidative stress occurs when the production of these reactive species overwhelms the body's antioxidant defenses. Research published in Antioxidant Activity examines this imbalance through diverse experimental approaches. Studies have investigated natural antioxidant sources including tea polysaccharides with hepatoprotective properties, cashew apple varieties harvested in Mexico, Surinamese medicinal plants with adaptogenic characteristics, and Argemone mexicana aerial parts extracted in different solvents. The journal has published work on the biochemical mechanisms underlying oxidative damage, including methylglyoxal formation from glucose metabolites and superoxide anion radical generation during cross-linking reactions. Applied research has explored antioxidant interventions in disease models, examining formulations in ulcerative colitis, cardiovascular disorders induced by L-NAME and high-fat diets, and metabolic syndrome management through micronutrient supplementation. Additional studies have assessed antioxidant compounds in cell-based systems, including HepG2 cells and H9c2 cardiomyoblast cells exposed to hydrogen peroxide-induced stress. This body of work addresses the critical role of oxidative stress in chronic disease pathology and evaluates potential therapeutic strategies through both natural product screening and mechanistic investigation of redox processes.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 92 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Free Radicals and Oxidative Stress, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Antioxidant Activity (ISSN 2471-2140).

Journal editorial board
Jie Yin · China Abdelnaser Elzaawely · Egypt Adnan Ayhanci · Turkey

This page summarises published research for orientation; it is not medical or professional advice.