Bionanotechnology is an interdisciplinary field that applies nanoscale materials and engineering principles to biological systems for diagnostic, therapeutic, and research purposes. Research published in Biomaterials on this topic has examined the use of engineered nanoparticles as delivery vehicles for genetic mate…
Bionanotechnology is an interdisciplinary field that applies nanoscale materials and engineering principles to biological systems for diagnostic, therapeutic, and research purposes. Research published in Biomaterials on this topic has examined the use of engineered nanoparticles as delivery vehicles for genetic material in neurological applications. Specifically, studies have investigated gold nanorods with varying surface properties as carriers for small interfering RNA targeting specific proteins in dopaminergic neuronal cells, evaluating how surface modifications affect gene silencing efficiency in controlled laboratory settings. This work addresses fundamental questions about how nanoparticle design parameters influence the ability to modulate gene expression in neurons, which has implications for understanding potential therapeutic strategies in neurological conditions. The field matters because nanoscale materials offer unique properties—including high surface-area-to-volume ratios, tunable surface chemistry, and the ability to cross biological barriers—that may enable more precise delivery of therapeutic agents to specific cell types. By characterizing how engineered nanoparticles interact with neuronal cells and affect molecular pathways, research in bionanotechnology contributes to the foundational knowledge needed to develop targeted interventions and advance our understanding of nanomaterial behavior in biological environments.
1 peer-reviewed article, ranked by relevance. Each links to its DOI.
The 1 article above has been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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