Breast tissue is the glandular and supporting structure of the mammary region, comprising lobules that produce milk, ducts that convey it to the nipple, and surrounding fibrous stroma and adipose tissue. Its architecture is hormonally responsive, remodeling across puberty, pregnancy, lactation, and involution under …
Breast tissue is the glandular and supporting structure of the mammary region, comprising lobules that produce milk, ducts that convey it to the nipple, and surrounding fibrous stroma and adipose tissue. Its architecture is hormonally responsive, remodeling across puberty, pregnancy, lactation, and involution under estrogen, progesterone, and prolactin signaling. Because epithelial cells of the terminal duct-lobular unit are the usual origin of malignancy, breast tissue is central to oncology, pathology, and reconstructive research. Histopathological assessment distinguishes benign processes such as idiopathic granulomatous mastitis, characterized by non-caseating granulomas and dense inflammatory aggregates, from carcinoma in situ and invasive disease, and increasingly relies on receptor and molecular profiling. Estrogen-receptor status, recurrence-risk genomic assays, and proteomic responses to targeted agents such as lapatinib inform the classification and management of hormone-driven tumors, while rarer entities including primary breast sarcoma and breast melanoma require distinct diagnostic and therapeutic approaches. The peer-reviewed studies indexed under this topic span granulomatous mastitis, receptor-defined carcinoma, recurrence scoring, proteomic and immunogenomic methods, and uncommon malignancies, reflecting the breadth of laboratory and clinicopathological investigation of breast tissue in health and disease.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 45 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Breast Tissue, linking to each citing work.