Research Topic · Peer-Reviewed

Chromosomal Dna

Chromosomal DNA is the deoxyribonucleic acid that constitutes the chromosomes, the principal carriers of genetic information in living cells. In eukaryotes it resides within the nucleus, where long double-stranded DNA molecules are wound around histone proteins and progressively folded with associated proteins into …

Curated from this journal's research 📚 11 peer-reviewed articles cited Cited 28× across the literature 🔖 ISSN 2575-7881 🗓 Reviewed July 2026

Overview

Chromosomal DNA is the deoxyribonucleic acid that constitutes the chromosomes, the principal carriers of genetic information in living cells. In eukaryotes it resides within the nucleus, where long double-stranded DNA molecules are wound around histone proteins and progressively folded with associated proteins into chromatin and, during cell division, into condensed chromosomes. Each DNA molecule is a sequence of nucleotide bases whose order encodes genes, the instructions for synthesising proteins and functional RNAs, interspersed with extensive regulatory and non-coding regions that govern when and how genes are expressed. Chromosomal DNA is faithfully replicated before cell division and accurately partitioned to daughter cells, ensuring the transmission of genetic information across cell generations and, through the germline, from parents to offspring; this inheritance underlies both the similarities and the variation among individuals and species. Its structure and composition, including features such as base composition and the clustering and arrangement of genes, influence genome organisation and function, and comparative analysis of chromosomal DNA illuminates evolutionary relationships. The integrity of chromosomal DNA is continually challenged by oxidative and other forms of damage, which cellular repair systems counteract; accumulated damage and changes such as telomere attrition are linked to ageing and disease. The study of chromosomal DNA spans molecular genetics, cytogenetics, and genomics, providing the foundation for understanding heredity, gene regulation, genome stability, and the molecular basis of biological diversity.

Research published in this journal

11 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 11 articles above have been cited 28 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Chromosomal Dna, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in DNA And RNA Research (ISSN 2575-7881).

Journal editorial board
jianhui zhang · United States Masayoshi Yamaguchi · United States Li Mao · United States

This page summarises published research for orientation; it is not medical or professional advice.