Research Topic · Peer-Reviewed

Signal Transduction Pathways

Signal transduction pathways are the molecular cascades through which cells detect extracellular signals and convert them into specific intracellular responses, enabling cells to sense and adapt to their environment. A pathway typically begins when a signalling molecule, such as a hormone, growth factor, cytokine, o…

Curated from this journal's research 📚 9 peer-reviewed articles cited Cited 64× across the literature 🔖 ISSN 3070-5657 🗓 Reviewed June 2026

Overview

Signal transduction pathways are the molecular cascades through which cells detect extracellular signals and convert them into specific intracellular responses, enabling cells to sense and adapt to their environment. A pathway typically begins when a signalling molecule, such as a hormone, growth factor, cytokine, or neurotransmitter, binds a receptor at the cell surface or within the cell. Receptor activation initiates a relay of biochemical events, frequently involving second messengers such as cyclic AMP, calcium ions, or inositol phosphates, and cascades of protein kinases and phosphatases that propagate and amplify the signal through reversible phosphorylation. These relays converge on effectors, including transcription factors, that alter gene expression, enzyme activity, cytoskeletal organisation, or membrane transport, producing the cellular response. Major pathways, such as those mediated by receptor tyrosine kinases, G-protein-coupled receptors, and developmental signalling systems, are organised into interconnected networks featuring crosstalk, feedback regulation, and signal integration. Through these mechanisms, signal transduction governs fundamental processes including proliferation, differentiation, metabolism, immune function, apoptosis, and embryonic development. Because precise control is essential, dysregulation of signalling components contributes to cancer, inflammatory and metabolic disease, and developmental disorders, and many such components are pharmacological targets. The study of signal transduction elucidates how molecular inputs are encoded, transmitted, and decoded to coordinate cellular behaviour within tissues and organisms.

Research published in this journal

9 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2022

A Review on Drug Design by the Application of Computer

S. Patil NikitaCorresponding author
Department of Pharmaceutics P.S.G.V.P.M’s College of Pharmacy, Shahada.
Exact topic Advanced Pharmaceutical Science And Technology doi:10.14302/issn.2328-0182.japst-22-4363

How this research is being cited

The 9 articles above have been cited 64 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Signal Transduction Pathways, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Embryology (ISSN 3070-5657).

Journal editorial board
Kei-ichiro Ishiguro · Japan Colin Ockleford · United Kingdom Thimios Mitsiadis · Switzerland

This page summarises published research for orientation; it is not medical or professional advice.