Cytotoxicity is the capacity of a substance to damage or kill living cells. The term is used widely in pharmacology, toxicology, and biomedical research to describe the harmful effects of chemicals, drugs, natural products, nanomaterials, and biological agents on cells. Measuring cytotoxicity is a fundamental step i…
Cytotoxicity is the capacity of a substance to damage or kill living cells. The term is used widely in pharmacology, toxicology, and biomedical research to describe the harmful effects of chemicals, drugs, natural products, nanomaterials, and biological agents on cells. Measuring cytotoxicity is a fundamental step in assessing the safety of new compounds and in screening for agents that selectively destroy unwanted cells, such as cancer cells. Laboratory cytotoxicity tests typically expose cultured cells to a test substance and then quantify cell viability, membrane integrity, or metabolic activity to determine how much of the substance is needed to harm or kill them. These in vitro assays allow researchers to compare the relative toxicity of different agents, identify therapeutic windows, and explore mechanisms of cell death. Experimental and Clinical Toxicology publishes peer-reviewed research that applies cytotoxicity testing across many contexts, including the antibacterial and cytotoxic activities of plant-derived compounds, the selective cytotoxicity of damsin derivatives in breast cancer cells, assessment of anticancer agents such as alendronate in breast cancer cells, evaluation of nanoparticle-based gene-silencing systems, and the toxicity of iodinated radiographic contrast agents. This page gathers open-access research relevant to cytotoxicity and the evaluation of cellular toxicity.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 68 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Cytotoxicity, linking to each citing work.