Research Topic · Peer-Reviewed

Implantation

Implantation is the process by which the developing blastocyst attaches to and embeds within the receptive endometrium, establishing the maternal-fetal interface necessary for pregnancy. It proceeds through apposition, adhesion, and invasion, and depends on synchronized endometrial receptivity—the implantation windo…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 101× across the literature 🔖 ISSN 2576-2818 🗓 Reviewed July 2026

Overview

Implantation is the process by which the developing blastocyst attaches to and embeds within the receptive endometrium, establishing the maternal-fetal interface necessary for pregnancy. It proceeds through apposition, adhesion, and invasion, and depends on synchronized endometrial receptivity—the implantation window—driven by hormonal priming, decidualization of stromal cells, and molecular crosstalk involving cytokines, adhesion molecules, and signaling by human chorionic gonadotropin. Successful implantation requires a competent embryo and a receptive uterus; failure is a major cause of infertility and recurrent pregnancy loss and a key determinant of outcomes in assisted reproduction. The peer-reviewed research collected here addresses reproductive aspects of implantation, including human chorionic gonadotropin signaling in decidualization and uterine receptivity, the clinical significance of mature-oocyte yield, ovarian stimulation strategies and live-birth rates in IVF, preconception immunological biomarkers in unexplained female infertility, and genetic markers associated with a fertility selection index. The term also denotes the surgical placement of biomaterials and devices, and related contributions examine bone-tissue repair during implantation of titanium-nickelide mesh, calcium-orthophosphate scaffolds for bone tissue engineering, and tissue-engineering constructs. Recurring themes include uterine receptivity and decidualization, embryo implantation in assisted reproduction, and biomaterial integration in implant surgery. Together these contributions frame implantation as a concept spanning reproductive biology and biomedical engineering, each centred on the establishment of a durable, functional interface between an introduced entity and host tissue.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 101 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Implantation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Fertility Biomarkers (ISSN 2576-2818).

Journal editorial board
Reshef Tal · United States Weihua Wang · United States

This page summarises published research for orientation; it is not medical or professional advice.