Research Topic · Peer-Reviewed

Golgi Apparatus

The Golgi apparatus is a membrane-bound organelle of eukaryotic cells that serves as the central hub for processing, modifying, sorting, and packaging proteins and lipids received from the endoplasmic reticulum. It consists of a polarized stack of flattened, fluid-filled cisternae organized into cis, medial, and tra…

Curated from this journal's research 📚 5 peer-reviewed articles cited Cited 36× across the literature 🔖 ISSN 2572-5424 🗓 Reviewed July 2026

Overview

The Golgi apparatus is a membrane-bound organelle of eukaryotic cells that serves as the central hub for processing, modifying, sorting, and packaging proteins and lipids received from the endoplasmic reticulum. It consists of a polarized stack of flattened, fluid-filled cisternae organized into cis, medial, and trans regions, together with the associated trans-Golgi network. Newly synthesized cargo enters at the cis face in transport vesicles, moves sequentially through the stack, and exits at the trans face packaged for delivery to the plasma membrane, lysosomes, secretory granules, or back to the endoplasmic reticulum. Within these compartments, resident enzymes carry out post-translational modifications that are essential to protein function, most notably the stepwise assembly and trimming of N-linked and O-linked glycans, as well as sulfation and proteolytic maturation. Through this glycosylation machinery the Golgi is intimately linked to glycomics and cellular metabolism, shaping the structures that govern protein folding, stability, trafficking, and cell-surface recognition. The organelle maintains its architecture through a balance of anterograde and retrograde vesicular transport mediated by coat proteins, tethers, and SNARE complexes, and it disassembles and reforms during cell division. Disruption of Golgi structure or glycosylation underlies congenital disorders of glycosylation and contributes to neurodegenerative and other diseases, making the organelle a focus of cell-biological and biomedical research.

Research published in this journal

5 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2012

Eukaryotic Signature Proteins

Han JianCorresponding author
Institute of Molecular BioSciences, Massey University, Palmerston North, New Zealand
Exact topic Proteomics and Genomics Research Cited by 5 doi:10.14302/issn.2326-0793.jpgr-12-101

How this research is being cited

The 5 articles above have been cited 36 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Golgi Apparatus, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Glycomics And Metabolism (ISSN 2572-5424).

Journal editorial board
Bassam Elgamoudi · Australia Carola Parolin · Italy Giuseppe Maurizio Campo · Italy

This page summarises published research for orientation; it is not medical or professional advice.