Research Topic · Peer-Reviewed

Polycythemia Vera

Polycythemia vera is a chronic blood cancer of the myeloproliferative neoplasm family in which the bone marrow overproduces red blood cells, and often white blood cells and platelets as well. The excess red cells thicken the blood, raising the risk of clotting, stroke, heart attack, and other vascular complications,…

Curated from this journal's research 📚 2 peer-reviewed articles cited Cited 1× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed July 2026

Overview

Polycythemia vera is a chronic blood cancer of the myeloproliferative neoplasm family in which the bone marrow overproduces red blood cells, and often white blood cells and platelets as well. The excess red cells thicken the blood, raising the risk of clotting, stroke, heart attack, and other vascular complications, and can cause symptoms such as headache, dizziness, itching, and an enlarged spleen. The disease is driven in the great majority of cases by an acquired mutation in the JAK2 gene, which causes blood-forming cells to proliferate independently of normal regulatory signals. Diagnosis relies on blood counts, JAK2 mutation testing, and bone marrow assessment, while management aims to reduce blood thickness and clotting risk through measures such as phlebotomy, low-dose aspirin, and cytoreductive drugs including hydroxyurea. Research relevant to this topic in Hematology and Oncology Research includes a case report of unusual cutaneous toxicity following prolonged hydroxyurea use in polycythemia vera, and a report describing the evolution of JAK2 V617F-negative idiopathic myelofibrosis into Philadelphia-positive chronic myeloid leukemia, both reflecting the journal's coverage of myeloproliferative disorders and their treatment. This page gathers peer-reviewed, open-access research relevant to polycythemia vera and related blood disorders.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Polycythemia Vera, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.