Coronavirus immunity refers to the protection against coronavirus infection or disease conferred by the immune system, whether acquired through natural infection, vaccination or passive transfer of antibodies. It involves humoral responses, notably neutralising antibodies directed against viral antigens such as the …
Coronavirus immunity refers to the protection against coronavirus infection or disease conferred by the immune system, whether acquired through natural infection, vaccination or passive transfer of antibodies. It involves humoral responses, notably neutralising antibodies directed against viral antigens such as the spike protein, and cellular responses, together with innate mechanisms including interferon signalling that shape the early course of infection. For SARS-CoV-2, immunity determines susceptibility to reinfection, the severity of disease and the population-level dynamics of transmission. Research relevant to this topic examines the use of immune modulators such as interferon-gamma, dietary approaches such as plant mannose-binding lectins intended to reduce infection risk, and the concept of herd immunity and the conditions under which it might limit spread. The durability and breadth of immunity are influenced by the molecular evolution of the virus, documented through spike-gene sequence analysis and lineage comparison, which can affect how well prior responses recognise new variants. Host factors and viral pathogenesis, including how affected cells and cytokine responses are regulated, further modulate protection. Understanding coronavirus immunity is therefore central to vaccine design, to interpreting the protection afforded by prior exposure, and to anticipating how immune escape by evolving variants may shape future risk.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 26 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Coronavirus Immunity, linking to each citing work.