Research Topic · Peer-Reviewed

Uric Acid

Uric acid is the final product of purine metabolism in humans, a waste compound formed when the body breaks down purines from cells and certain foods, which is filtered by the kidneys and excreted mainly in urine. When uric acid is produced in excess or inadequately excreted, blood concentrations rise (hyperuricemia…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 97× across the literature 🗓 Reviewed June 2026

Overview

Uric acid is the final product of purine metabolism in humans, a waste compound formed when the body breaks down purines from cells and certain foods, which is filtered by the kidneys and excreted mainly in urine. When uric acid is produced in excess or inadequately excreted, blood concentrations rise (hyperuricemia), which can lead to the deposition of urate crystals in joints, causing gout, and to the formation of uric-acid kidney stones. Within urology, uric acid is of particular interest because of its role in stone disease and its handling by the urinary tract. Research collected here includes the use of dual-energy computed tomography to characterize and guide the management of uric-acid renal calculi, distinguishing them from other stone types, and the clinical management of hyperuricemia. The enzyme xanthine oxidase, which catalyzes the final steps of uric-acid formation, is also studied, as is the measurement of total antioxidant status, reflecting uric acid's dual identity as both a metabolic waste product and a circulating antioxidant. Related work addresses metabolic and cardiovascular conditions, obesity, and oxidative stress that frequently accompany altered urate handling. Together these topics illustrate how uric acid links purine metabolism, stone formation, and broader metabolic health within urological research.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 97 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Uric Acid, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Medical and Surgical Urology.

Journal editorial board
Paul Rusilko · United States Ilke Beyitler · Cyprus Rifat Hamoudi · United Arab Emirates

This page summarises published research for orientation; it is not medical or professional advice.