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Mar 2014 DOI 10.14302/issn.2372-6601.jhor-13-352
O’ Sullivan JMCorresponding author
Department of Haematology, Cork University Hospital, Cork, Ireland
Variation in the lower and upper limits of haemoglobin (Hb) ranges will alter diagnosis and referral rates of anaemia or erythrocytosis. The haemoglobin ranges for adults in Irish laboratories were applied in the context of haemoglobin levels of a representative sample of Irish adults (SLAN). Between 2.8% and 8.5% of men would be diagnosed with anaemia in different laboratories for lower limit between 130-140g/L. For women, diagnosis of anaemia would range from 0.7% to 7.3% for the lower limit between 110-125g/L. Similar reference range variations occur in UK laboratories. A suggested “normal reference range” is extrapolated from the SLAN cohort.
Feb 2022
K Al Miraj ACorresponding author
Research Assistant, Department of Vascular Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU)Dhaka, Bangladesh.
Introduction Calcium (Ca2+) plays an important role in the pathogenesis of ischemic cell damage. Intracellular Ca2+ accumulation leads to neuronal damage by triggering the cycle of cytotoxic events, however the relationship of serum Ca levels and the pathways involved in ischemic injury is unclear. Aim of Study To investigate the relationship of serum Ca2+ levels with severity of acute ischaemic stroke, serum calcium (Ca2+) levels were measured within the first 48 hours and were compared with the clinical severity of acute ischaemic stroke. Material and Methods A hospital based cross sectional study was performed among 100 patients of acute ischaemic stroke who fulfilled the inclusion criteria. The Study was done from July 2020 to August 2021 in SPRC & Neurology Hospital Dhaka, Bangladesh And BSMMU Hospital Dhaka, Bangladesh. After hospitalization presenting complaints, physical findings of the patients were recorded. Severity of stroke was measured by NIHSS scale. Serum calcium level of every patient was measured. Calcium level was divided into 3 groups by weighted average. Statistical analysis was carried out by a non-parametric Ruska Wallis test. Results Among the 100 patients 59% were male. Among all patients 57% of patients were found to be smokers (98% male, 2% female). Among all patients 63% patients were found hypertensive and 21% of all patients (24% male, 17% female) were diabetic. Mean cholesterol level was 257.98mg/dl with standard deviation 55.49 which is above the reference range suggesting hypercholesterolemia, Triglyceride was borderline and LDL cholesterol was slightly higher and HDL cholesterol was slightly lower. Calcium level was divided into 3 groups and NIHSS score was calculated for every patient in each group. The median NIHSS score for group1 (calcium level ≤8.8 mg/dl) was 9(2-20), for group 2 (calcium level 8.9-9.6 mg/dl) was 6 (1-17) and for group 3 (calcium level ≥9.7mg/dl) was 4 (1-16). Conclusion Commonest risk factor of ischaemic stroke is hypertension. Other risk factors are smoking, diabetes mellitus and hyperlipidemia, cardiac disease. Higher serum calcium level is associated with less severity of ischaemic stroke.
Aug 2017 DOI 10.14302/issn.2576-2818.jfb-17-1595
El-Zahar HebaCorresponding author
Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Egypt.
The postpartum period in camel are considered the most critical period for camel's health and for future fertility. The objective of the present study was to compare the clinical examination results and the concentration of hemoglobin, total protein, calcium and progesterone at different instances (1st, 3rd and 9th days) postpartum. Fifteen female camels during the postpartum period (1st, 3rd and 9th days) were included in the present study. Hematological, biochemical profiles and ultrasonographic examination were performed. The clinical examination results were normal and no evidence of clinical disease. The results of the hematological and biochemical findings were within the reference range obtained previously by our research team. The concentrations of hemoglobin, total protein, calcium and progesterone were measured at the 1st, 3rd and 9th days postpartum. Hemoglobin concentration differs significantly in the 3rd day (p=0.012) compared to the 1st day postpartum. Total protein showed significant increase in the 3rd day (p=0.003) compared to the 1st day postpartum. Calcium concentration showed significant increase in the 9th day (p=0.002) compared to the 1st and the 3rd days postpartum. Progesterone concentration showed significant decrease in the 9th day (p=0.004) compared to the 1st and the 3rd days postpartum. The ultrasonographic imaging of the uterus and ovaries showed normal uterine involution and no abnormal secretions in the uterus. It is concluded that, clinical examination, hematological and biochemical profiles are very important tools for monitoring female camels during postpartum period.