Search results for “accidents

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4 articles
Skeletal Muscle Open Access

BaMtox, a Myotoxic Enzyme Isolated from the Venom of the Bothrops Alternatus

Mar 2022 DOI 10.14302/issn.2832-4048.jsm-21-3986
Fernando Moreira Izidoro LuizCorresponding author Faculdade de Medicina, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.

Snake envenomations are responsible for a high percentage of deaths, as these toxic proteins induce severe local and systemic effects. In Brazil, the Bothrops genus is responsible for a satisfactory fraction of accidents, including Bothropsalternatus, recognized as urutu, whose venom is capable of inducing severe myotoxicity. In this work, the BaMtox toxin was purified through a combination of three chromatographic steps, ion exchange in DEAE-Sepharose, affinity in Benzamidine Sepharose 6B columns and reversed-phase HPLC chromatography on a C18 column. The BaMtox toxin has a molecular mass of approximately 14kDa and did not show phospholipase activity or hemorrhage. On the other hand, it induced edema and a significant increase in plasma levels of the creatine kinase enzyme. Thus, the protein called BaMtox is able to induce myotoxicity.

Favourable Outcome in Pediatric Neurosurgery for Extra Dural Hematoma in Sub Sahara Africa: Report of Parakou University Hospital in the Benin Republic

Dec 2020 DOI 10.14302/issn.2470-5020.jnrt-20-3629
K QuenumCorresponding author Neurosurgery Departement of Parakou University Chud/Ba, Republic of Benin

Introduction The extra dural hematoma is a blood collection between the cranial vault and the dura mater. It is a neurosurgical emergency whose statistical data are poorly known in the Republic of Benin. Objective The aims of this study are to assess epidemiology, therapeutic and outcome of traumatic extra dural hematomas for children admitted to the surgical department of CHUD-B/A from 2012 to 2017. Methods This was a cross-sectional, descriptive and retrospective study over a period from January 1st, 2012 to December 31st, 2017. Results One hundred and seventy-eight cases of children aged between 0-15 years were examined for brain traumatic injury. Twenty-seven 27 (15.2%) cases of extra dural hematomas were retained. The most represented age group was between 11-15 years with a frequency of 42.1%. The male sex was more represented (78.9%). Road traffic accidents were the main aetiology (57.9%). 52.6% had a mild head injury, 26.3% had a moderate head injury and 21.1% had a severe head injury. On brain scan the frequently observed location was temporo-parietal (31.6%). Acute anemia was observed in 16 children. Seventeen children were operated on. The operation involved evacuation of extra dural hematoma by cranial bone flap with suspension of the dura mater. There were no deaths. Conclusion The availability of brain CT makes the diagnosis of extra dural hematoma easier. Its management is neurosurgical with a favourable post-operative evolution in all cases in this series.

Motorcycle-Related Head and Limbs Injuries from Road Traffic Accident at a Second Level Hospital in Cameroon

Mar 2019 DOI 10.14302/issn.2474-3585.jpmc-19-2633
ErickTandi TinyamiCorresponding author Department of Preventive Medicine, College of Medicine, Graduate School of Public Health Korea University, Seoul South Korea.

Motorcycles have been increasing used widely in various urban, suburban and villages in Cameroon with an increased in accidents resulting to injuries among the population. Head and limbs injuries are responsible for most of the cases encountered from related crashes. A prospective study on head and limbs injuries resulting from motorcycle crash were assessed among the different cases brought to the casualty and emergency department of the Kumba district hospital. Most of the injured cases were of motorcycle and other vehicle collisions 203 (47.65) and the least among motorcycle lone crash 51 (11.97). Motorcycle to motorcycle collisions accounted for 107 (25.12 %) of the cases. 65 (15.26%) were motorcycle with pedestrians related collision. Stepping up and facilitating the regulations on licenses and the use of personal protective equipment for riders, improvement of roads infrastructures with pedestrian path, expanding health facilities and equipment, and human resources for health as well as empowering the population on road safety measures will be very important for RTAs control measures of the nation.

Increase Writing Performance using A Shaping Procedure with a Patient with Sequelae Caused by Cardiovascular Accident

Jun 2017 DOI 10.14302/issn.2474-7785.jarh-17-1575
Renaux CharlotteCorresponding author Univ.Lille, CNRS, UMR9193 – SCALab – Sciences Cognitives et Sciences Affectives, F-59000 Lille, France ;

Background and Objective: Behavioral procedures have proven to be effective with elderly adults in nursing home. The purpose of this study was to evaluate the effectiveness of a shaping procedure as a means of increasing writing performance. More specifically, our aim was to reeducate a motor behavior in a patient for whom the behavior was no longer present. Materials and Methods: The participant was an elderly (76-year-old) who had sequelae from a cardiovascular accident since 2011, and was asked to write some selected words. Data were collected though face-to-face interviews then analyzed using cotation methods. Results: The shaping and chaining procedures were efficient and performance of writing increased, even for infrequent words. Conclusion: Increasing writing performance is possible for the elderly people, even if they have suffered from cardiovascular accidents in the past. Here we used a successful brief shaping procedure to enhance quickly that ability.

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