Research Topic · Peer-Reviewed

Knee Osteoarthritis

Knee osteoarthritis is a degenerative joint disease in which the cartilage cushioning the knee gradually breaks down, leading to pain, stiffness, swelling and reduced range of motion as the underlying bones are increasingly affected. It is one of the most common chronic musculoskeletal conditions, particularly among…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 4× across the literature 🗓 Reviewed June 2026

Overview

Knee osteoarthritis is a degenerative joint disease in which the cartilage cushioning the knee gradually breaks down, leading to pain, stiffness, swelling and reduced range of motion as the underlying bones are increasingly affected. It is one of the most common chronic musculoskeletal conditions, particularly among older adults, and its risk is increased by ageing, obesity, previous joint injury and mechanical overload; while there is no cure, management aims to relieve symptoms, preserve function and maintain quality of life. Research on knee osteoarthritis spans risk factors, comorbidity and conservative and pharmacological management. Studies in this journal's corpus examine non-pharmacological approaches such as Tai-Chi exercise training in older adults with painful knee osteoarthritis, and the evaluation of investigational therapies in randomized trials. A substantial body of related work situates osteoarthritis within broader health concerns of ageing, including its associations with falls, frailty, sarcopenia, depression and the potential role of vitamin D, as well as possible links to overweight, intramuscular fat and infection risk after joint arthroplasty. Together these aspects span pathology, epidemiology, exercise and rehabilitation, comorbidity and prevention, reflecting an emphasis on managing osteoarthritis as a chronic condition that affects mobility and overall wellbeing, especially in older populations.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 4 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Knee Osteoarthritis, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Osteoarthritis and Cartilage.

Journal editorial board
Giuseppe Maurizio Campo · ISRAEL

This page summarises published research for orientation; it is not medical or professional advice.