Genome Analysis

Overview

Genome analysis is the systematic study of an organism's genetic material, encompassing the sequencing, assembly, annotation and comparative interpretation of genomes to characterise genes, regulatory elements and sequence variation. It identifies coding and non-coding regions, detects polymorphisms and mutations, infers phylogeny and evolutionary conservation, and links genomic features to phenotype, disease and adaptation. Modern genome analysis is computationally intensive, drawing on bioinformatics for alignment, variant calling, functional prediction and the integration of genomic data with transcriptomic and proteomic information. Research relevant to this area includes bioinformatic analysis of coronary-disease-associated SNPs and genes implicated in atherosclerosis; phylogenetics, protein-domain conservation and gene architecture of the RBM45 gene across Metazoa; the proteomics and bioinformatics status of the Human Proteome Project; immunogenomic approaches for monitoring cancer and infectious disease; label-free proteomic and molecular analysis of a parasitic organism; bioinformatics of metabolomics in type 2 diabetes; and integrated proteomic and genomic techniques for diagnostics and personalised medicine. Studies of signature proteins, epigenetics and nutrition, and gene-architecture conservation further illustrate how sequence-level analysis informs biological interpretation. The field connects genomics, evolutionary biology and bioinformatics, using genome structure and variation to explain gene function, evolutionary relationships and the molecular basis of health and disease across species.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 62 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• Ecological drivers of Promethearchaeati’s specialization for deep subsurface environments
  2026 · Communications Biology
• Peripheral biomarkers of neuroinflammation in Alzheimer’s disease and vascular dementia
  2026 · Biochemical Pharmacology
• Association of peripheral blood NLRP3, sTREM2, and p-tau217 levels with cognitive outcomes in patients with chronic alcohol-related brain damage
  2026 · Alcohol and Alcoholism
• Chronic alcohol consumption induces phenotypic and functional alterations consistent with a hyper-inflammatory state in peripheral blood mononuclear cell-derived microglia in a rhesus macaque model
  Hami Hemati et al. · 2025 · Brain, behavior, and immunity
• A comprehensive genome-wide analysis for signatures of selection in goat (genus Capra) revealed new candidate genes for environmental adaptation and productive traits
  2025 · BMC Genomics
• Improving T2D machine learning-based prediction accuracy with SNPs and younger age
  2025 · Computational and Structural Biotechnology Journal
• Investigation of Aldose Reductase Inhibitors: Implications for Therapeutic Targets in Diabetic Retinopathy
  2025 · Journal of Molecular Structure
• Chronic alcohol consumption induces phenotypic and functional alterations consistent with a hyper-inflammatory state in peripheral blood mononuclear cell-derived microglia in a rhesus macaque model
  2025 · Brain Behavior and Immunity

A sample of recent works citing this journal's research on Genome Analysis, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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