The journal connects cancer initiation, progression, heterogeneity, metastasis, treatment response, and resistance with biomarker discovery, characterisation, and validation. Manuscript fit is determined by the central scientific contribution, not by the use of a particular assay, dataset, or technique alone.
Cancer geneticsInherited or acquired genetic changes involved in cancer initiation, progression, heterogeneity, metastasis, and treatment resistance.
Cancer genomicsGenome-scale investigation of cancer-associated alterations, including integration with transcriptomic, epigenomic, proteomic, metabolomic, single-cell, or spatial data.
Hereditary cancerThe germline-predisposition branch of cancer genetics, distinct from tumor-only somatic profiling.
Biomarker scienceDiscovery, measurement, characterisation, and validation of cancer-related indicators for risk, detection, diagnosis, prognosis, prediction, monitoring, or response.
Molecular & precision oncologyThe application context linking molecular mechanisms and biomarkers to cancer classification, prevention, diagnosis, treatment selection, or resistance.
Translational researchWork connecting discovery or mechanism with human investigation or clinical use; not every basic-science study must already demonstrate clinical utility.