Journal of Cancer Genetics And Biomarkers

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Journal of Cancer Genetics and Biomarkers

Aims & scope

Cancer-specific research with genetics, genomics, molecular mechanisms, or biomarker science at its core.

JCGB considers laboratory, computational, population, translational, and clinical studies when that scientific anchor makes a substantive contribution to the research question, methods, and interpretation.

Scholarly purpose

From cancer mechanism to measurable evidence

JCGB provides a focused home for research that explains how inherited and acquired molecular changes shape cancer, and for work that develops or evaluates biomarkers for a defined research or clinical purpose.

The journal connects cancer initiation, progression, heterogeneity, metastasis, treatment response, and resistance with biomarker discovery, characterisation, and validation. Manuscript fit is determined by the central scientific contribution, not by the use of a particular assay, dataset, or technique alone.

Cancer geneticsInherited or acquired genetic changes involved in cancer initiation, progression, heterogeneity, metastasis, and treatment resistance.
Cancer genomicsGenome-scale investigation of cancer-associated alterations, including integration with transcriptomic, epigenomic, proteomic, metabolomic, single-cell, or spatial data.
Hereditary cancerThe germline-predisposition branch of cancer genetics, distinct from tumor-only somatic profiling.
Biomarker scienceDiscovery, measurement, characterisation, and validation of cancer-related indicators for risk, detection, diagnosis, prognosis, prediction, monitoring, or response.
Molecular & precision oncologyThe application context linking molecular mechanisms and biomarkers to cancer classification, prevention, diagnosis, treatment selection, or resistance.
Translational researchWork connecting discovery or mechanism with human investigation or clinical use; not every basic-science study must already demonstrate clinical utility.
Research areas

What JCGB publishes

The following groups describe the journal's core scientific territory. They are representative rather than an exhaustive keyword list.

01 / GENOME BIOLOGY

Cancer genetics & genomics

Somatic drivers, tumor-suppressor alterations, DNA repair, genomic instability, mutational processes, chromosomal alterations, inherited predisposition, and germline variant interpretation.

02 / DYNAMICS

Tumor evolution & therapeutic response

Clonal evolution, intratumor heterogeneity, metastasis, therapy-driven selection, acquired resistance, pharmacogenomics, molecular targets, and synthetic-lethal relationships.

03 / MEASUREMENT

Cancer-biomarker science

Discovery, assay characterisation, analytical and clinical validation, context-of-use evaluation, and biomarkers for risk, detection, diagnosis, prognosis, prediction, monitoring, minimal residual disease, or response.

04 / INTEGRATION

Molecular & functional research

Epigenetics, transcriptomics, non-coding RNA, proteomics, metabolomics, multi-omics, functional genomics, model systems, single-cell and spatial genomics, and molecularly grounded microenvironment or immune research.

Scope examples identify scientific themes; they do not guarantee editorial acceptance.

Study settings

Research approaches within scope

Different study settings are considered when the cancer-genetics, molecular-mechanism, or biomarker contribution remains central and the evidence is appropriate to the claim.

Laboratory & preclinicalMechanistic studies of cancer-associated alterations, pathways, targets, model systems, assay development, or treatment resistance.
Computational & multi-omicsAnalyses that produce interpretable cancer-biological or biomarker insight and include suitable evaluation, benchmarking, or validation.
Clinical & translationalPatient-based studies in which molecular or biomarker evidence is integral to the research question and conclusions.
PopulationResearch on cancer risk or outcomes anchored in inherited susceptibility, molecular epidemiology, genomic determinants, gene-environment interaction, or population biomarker validation.
Methods & technologiesAssays, analytical methods, or computational approaches whose utility is demonstrated for a defined cancer-genetics, genomics, or biomarker question.
Author fit guide

Is your manuscript within scope?

The scientific anchor matters more than the discipline label. Use these boundaries before choosing a submission format.

Clearly within scope

  • Cancer-specific work with a central genetic, genomic, or molecular-mechanistic contribution.
  • Biomarker discovery or validation with a defined purpose or context of use.
  • Functional or computational studies tied to cancer mechanism or biomarker utility.
  • Clinical, translational, or population research with integrated molecular evidence.

Outside scope

  • Non-cancer biomarkers or genetics research without a cancer endpoint.
  • Treatment protocols, routine management, or outcomes without molecular or biomarker insight.
  • Imaging, pathology, or diagnostic descriptions without molecular integration.
  • Health-services, cost, access, or policy research without a cancer-genetics or biomarker question.
  • Generic AI, computational, or technical work without a defined cancer question and suitable evaluation.

Fit depends on the scientific anchor

AI and machine learning, imaging or radiogenomics, microbiome research, tumor-microenvironment studies, treatment-response studies, technology papers, and case-based work may fit when the cancer-genetics, molecular, or biomarker contribution is substantive and appropriately supported. For an uncertain case, ask a scope question before submission.

Examples of fit

Research questions JCGB is positioned to consider

These questions illustrate the journal's scope; they are not article titles or promises of acceptance.

Cancer mechanismWhich somatic or germline alterations drive cancer initiation, progression, metastasis, or resistance?
Clonal dynamicsHow do clonal, single-cell, or spatial patterns change during disease progression or treatment?
Biomarker evidenceCan a candidate biomarker be measured reliably and validated for an explicit research or clinical context?
Methods & modelsHow do functional or computational findings clarify cancer mechanism or support a biomarker strategy?
Clinical translationWhich molecular features inform prognosis, therapeutic response, recurrence, or minimal residual disease?
Manuscript formats

How suitable research may be presented

Suitable work may use several scholarly formats. The current Author Instructions control exact category names, eligibility, structure, and preparation requirements.

Original researchExperimental, computational, population, translational, or clinical investigations that meet the central scope requirement.
Reviews & evidence synthesesCritical or systematic syntheses that clarify cancer mechanisms, biomarker performance, validation, or translational relevance.
Methods & protocolsAssay, technical, or computational approaches demonstrated in a defined cancer-genetics, genomics, or biomarker application.
Concise & specialised workAuthors considering rapid or short reports, case-based work, perspectives, editorials, policy analysis, or data/resource formats should confirm current eligibility before submission.

Confirm the current submission category

Before preparing a manuscript, consult the JCGB Author Instructions. If a specialised format is not clearly covered there, contact the publisher before submission.

Scholarly community

Authors, readers & professional audiences

The scope is relevant to researchers and professionals whose cancer work has a substantive genetic, genomic, molecular, or biomarker foundation.

Authors

Cancer geneticists and genomicists, molecular and translational oncology researchers, biomarker scientists, molecular pathologists, clinical laboratory researchers, and molecular epidemiologists.

Readers

Researchers interpreting cancer mechanisms, hereditary risk, molecular diagnostics, prognosis, treatment response, resistance, and biomarker evidence.

Methods communities

Bioinformaticians, computational and systems biologists, assay developers, and clinical or population researchers working with cancer-linked molecular data.

Before submission

A five-question fit check

A manuscript is more likely to meet the journal's stated remit when all five questions can be answered clearly.

01Is cancer the primary context?The disease question, cohort, model, or intended application should be cancer-specific.
02Is the scientific anchor central?Genetics, genomics, molecular mechanism, or biomarker science should shape the question, analysis, and interpretation.
03Is the biomarker purpose clear?For biomarker work, identify the intended purpose or context of use and distinguish discovery from validation.
04Does the evidence support the claim?Use methods, comparisons, evaluation, and validation appropriate to the strength of the conclusion.
05Have current requirements been checked?Confirm the submission category, reporting expectations, policies, and charges on their controlling pages.
Submit to JCGB

Does your manuscript fit JCGB?

Review the current author instructions, then submit through ManuscriptZone. If the molecular or biomarker contribution is uncertain, contact the publisher before submission.

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